Publications

  • Zhao, J.H., Stacey, D., Eriksson, N., Macdonald-Dunlop, E., Hedman, Å.K., … & Peters, J.E. (2023).
    Mapping pQTLs of circulating inflammatory proteins identifies drivers of immune-mediated disease risk and novel therapeutic targets.
    Nature Immunology.Αrticle link
  • Repetto, L., Chen, J., Yang, Z., Zhai, R., Timmers, P., … & Shen, X. (2023).
    Genetic mechanisms of 184 neuro-related proteins in human plasma.
    medRxiv 2023.02.10.23285650.Αrticle link
  • Donovan K., Herrington W., Paré G., Pigeyre M., Haynes R., Sardell R., Butterworth A., Folkersen L., Gustafsson S., Wang Q., Baigent C., Mälarstig A., Holmes M., Staplin N. (2023).
    Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: a Mendelian Randomization study.
    Clinical Journal of the American Society of Nephrology, 18(1), 17-27.Αrticle link
  • Yang Z., Macdonald-Dunlop E., Chen J., Zhai R., Li T., Richmond A., Klarić L., … & Shen X. (2022).
    Genetic Landscape of the ACE2 Coronavirus Receptor.
    Circulation, 145(18), 1398-1411. Αrticle link
  • Bourgonje, A.R., Hu, S., Spekhorst, L.M., Zhernakova, D.V., Vich Vila, A., Li, Y., … & Weersma, R.K. (2022). 
    The effect of phenotype and genotype on the plasma proteome in patients with Inflammatory Bowel Disease. 
    Journal of Crohn’s and Colitis, 16(3), 414-429. Αrticle link

  • Macdonald-Dunlop, E., Klarić, L., Folkersen, L., Timmers, P. R., Gustafsson, S., Zhao, J. H., … & Wilson, J. F. (2021). 
    Mapping genetic determinants of 184 circulating proteins in 26,494 individuals to connect proteins and disease. 
    medRxiv 2021.08.03.21261494. Αrticle link

  • Lind, L., Gigante, B., Borné, Y., Feldreich, T., Leppert, J., Hedberg, P., … & Mälarstig, A. (2021). 
    Plasma protein profile of carotid artery atherosclerosis and atherosclerotic outcomes: meta-analyses and mendelian randomization analyses. 
    Arteriosclerosis, Thrombosis, and Vascular Biology, 41(5), 1777-1788. Αrticle link

  • Smith-Byrne, K., Chen, Y., Kachuri, L., Kapoor, P. M., Guida, F., Zahed, H., … & Malarstig, A. (2021). 
    IL-18 and Lower Risk for Lung Cancer: Triangulated Evidence from Germline Predictions, Pre-Diagnostic Measurements, and Tumor Expression. 
    medRxiv 2021.03.26.21254400. Αrticle link

  • Klaric, L., Gisby, J. S., Papadaki, A., Muckian, M. D., Macdonald-Dunlop, E., Zhao, J. H., … & Peters, J. E. (2021). 
    Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19. 
    medRxiv 2021.04.01.21254789. Αrticle link

  • Gisby, J., Clarke, C. L., Medjeral-Thomas, N., Malik, T. H., Papadaki, A., Mortimer, P. M., … & Peters, J. E. (2020). 
    Longitudinal proteomic profiling of high-risk patients with COVID-19 reveals markers of severity and predictors of fatal disease. 
    medRxiv 2020.11.05.20223289. Αrticle link

  • Pietzner, M., Wheeler, E., Carrasco-Zanini, J., Raffler, J., Kerrison, N. D., Oerton, E., … & Langenberg, C. (2020). 
    Genetic architecture of host proteins involved in SARS-CoV-2 infection. 
    Nature communications, 11(1), 1-14. Αrticle link

  • Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, Å. K., Schork, A., … & Mälarstig, A. (2020). 
    Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. 
    Nature metabolism, 2(10), 1135-1148. Αrticle link | Read more about the SCALLOP pQTL CVD I study on: SCALLOP news post and KI news.

  • Suhre, K., McCarthy, M. I., & Schwenk, J. M. (2020). 
    Genetics meets proteomics: perspectives for large population-based studies. 
    Nature Reviews Genetics, 1-19. Αrticle link

  • Bretherick, A. D., Canela-Xandri, O., Joshi, P. K., Clark, D. W., Rawlik, K., Boutin, T. S., … & Haley, C. (2020). 
    Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits. 
    PLoS genetics, 16(7), e1008785. Αrticle link

  • Folkersen, L., Gustafsson, S., Wang, Q., Hansen, D. H., Hedman, A. K., Schork, A., … & Malarstig, A. (2020). 
    Genomic evaluation of circulating proteins for drug target characterisation and precision medicine. 
    BioRxiv 2020.04.03.023804. Article link | Read about the author’s perspective on the SCALLOP pQTL CVD I study on this SCALLOP news post

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  • Folkersen, L., Fauman, E., Sabater-Lleal, M., Strawbridge, R. J., Frånberg, M., Sennblad, B., … & Mälarstig, A. (2017). 
    Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease. 
    PLoS genetics, 13(4), e1006706. Αrticle link

  • Enroth, S., Johansson, Å., Enroth, S. B., & Gyllensten, U. (2014). 
    Strong effects of genetic and lifestyle factors on biomarker variation and use of personalized cutoffs. 
    Nature communications, 5(1), 1-11. Αrticle link